Council for Responsible Nutrition
Home
| Who is CRN? | About Dietary Supplements | Industry Regulation | Press Room | Annual Conference | Members Only

General Information

Vitamins and Minerals >
Herbal and Botanical Supplements
Sports Nutrition Supplements
Specialty Supplements
The Dietary Supplement Pyramid
How to Read a Supplement Label
CRN Publications
Safety of Vitamins and Minerals
Are dietary supplements safe for people with G6PD deficiency?

• Find out more


General information on Safety:

• Click here to download a table from The Safety of Vitamins and Minerals, 2nd Edition, with information on values from the US Food and Nutrition Board, the European Commission, the United Kingdom Expert Group on Vitamins and Minerals, and Japan (PDF)

• Click here for full publication, The Safety of Vitamins and Minerals, 2nd Edition

CRN Upper Levels for Supplements (ULS)

Nutrient

CRN ULS2 2004

Vitamin A
(retinol and its esters)

3,000 µg4 (10,000 IU)
1,500 µg5
(5,000 IU)

Beta-carotene

25 mg nonsmokers
(Smokers should not use.)

Vitamin D

60 µg (2,400 IU)

Vitamin E

1,000 mg (1,600 IU)

Vitamin K

10 mg

Vitamin C

2,000 mg

Vitamin B1

100 mg

Vitamin B2

200 mg

Nicotinic acid

500 mg 6 and 250 mg SR7

Nicotinamide

1,500 mg

Vitamin B6

100 mg

Folic acid

1,000 µg

Vitamin B12

3,000 µg

Biotin

2,500 µg

Pantothenic acid

1,000 mg

Calcium

1,500 mg

Phosphorus

1,500 mg

Magnesium

400 mg

Potassium

1,500 mg (3 x 500)

Boron

6 mg

Chromium

1,000 µg (any form of Cr III)

Copper

9 mg

Fluoride

No ULS (UL= 6 mg)

Iodine

500 µg

Iron

60 mg (full stomach)

Manganese

10 mg

Molybdenum

350 µg

Selenium

200 µg

Zinc

30 mg

 

1See Appendix for Table of Comparison of CRN ULS, US FNB UL, EC SCF UL, UK EVM SUL or GL, and Japan UL

2ULS = CRN's Upper Level for Supplements (specific for supplements)

3UL = Tolerable Upper Intake Level (applies to total intake unless specified otherwise)

4Retinol ULS for persons with average levels of dietary retinol

5Retinol ULS for persons consuming liver or foods fortified with retinol

6Based on liver and gastrointestinal toxicity

7SR = slow-release (time-release) formulations of nicotinic acid

8UL for niacin applies to both nicotinic acid and nicotinamide

9Based on vasodilative flushing reaction

 


1828 L Street, NW, Suite 510 • Washington, DC, 20036-5114 • (202) 204-7700 fax (202) 204-7701 • e-mail webmaster@crnusa.org